Oncotarget; the Oncology Medical Journal

Oncortarget is a reputable medical journal. Its content is derived from variety researches related to oncology. Oncology refers to a medical branch which deals with treatment, prevention, and diagnosis of cancer.

Oncotarget’s expedition

Oncortarget was first published in the year 2010. Its current publishers are Impact Journals. The publication is only available in the English language. Due to public demand, Oncotarget makes releases on a weekly basis.

The unique factor about this publication is it is an open access journal. Therefore anyone interested in Oncology news can read it online, financial, technical or legal barriers notwithstanding. The main editorial team is made up of two enthusiastic individuals, Mikhail Blagosklonny and Andrei V. Gudkov. Read more at dovepress.com.

Mikhail Blagoskylonny and his career in Oncology

Mikhail Blagosklonny is a famous scientist and professor who has spent a very great time of his life studying cancer and aging. He currently shares his knowledge and research findings with students at Rosewell Park Cancer Institute in New York

Mr. Blagoskylonny is a man of diverse knowledge and skills. He earned both his medical degree in Internal Medicine and Doctor of Philosophy in Medicine and Cardiology at the First Pavlov State Medical University of St. Peterburg. Mikhail’s skills enabled him to get appointed as the associate professor of Medicine at New York Medical College.

Before Mikhail became a professor, he worked as a senior scientist at Ordway Research Institute. Professor Blagoskylonny’s diverse research interest include cancer therapy and mechanisms of aging.

Mikhail’s advocacy in longevity research

Mikhail Blagoskylonny has conducted several types of research. He has come up with a hypothesis which highlights the possible role of TOR signaling in cancer and aging. He went ahead and proposed a popular cancer drug could cause full treatment and offer life extension.

Mikhail’s editorial ventures

Besides being a chief editor at Oncotarget, Mikhail Blagoskylonny is also editor in chief of Cell Cycle and Aging. Mikhail is as well an associate editor of Cancer Biology and Therapy. Cell Death and Differentiation editorial board also have Professor.

Blagoskylonny as an active member.

Professor Mikhail is a renowned author and has published over three hundred articles and journals related to Oncology.

Can Exercise Magically Alter Our DNA?

Although the thought of our DNA changing through exercise sounds like an advanced magic act preformed within the body, it can be explained scientifically. A new study sheds some light on just how exercise translates into a more physically healthy body. Let’s just say the human genome knows how to preform one heck of a believable magic trick!

So what’s really happening here? Scientist have known for a long time that genes within the body are constantly changing, turning off and on, all dependent on what biochemical signals they receive. We now know, thanks to new research, that exercise changes the shape and functioning of our genes. We now have a better idea of how the genes respond to physical activity.

The study published recently in Epigenetics (changes occurring outside of the gene which changes their operation) proves that exercise creates new patterns of methylation. Methylation makes the gene more or less likely to respond to biochemical signals from the body by attaching clusters of atoms to the outside of the gene.

In the study, 23 men and women were recruited to exercise one leg by pedaling for 45 minutes, four times a week for three months. Each participant then had a muscle biopsy taken from both legs. The exercised leg showed the methylation changes, while the unexercised leg did not. These changes happened in the part of the genome called “enhancers” that can amplify the gene’s expression of proteins. These genes affect our muscle health.

So, while it’s easy to see the process of exercise altering your Dour as pure magic, there is scientific research that gives us a better understanding. Someone who is a strong believer in exercise is Susan McGalla. She explains more here in her article.

Best Way to Create Healthy Exercise Habits

Incorporating daily exercise into a busy lifestyle is challenging but many factors must be taken into account when creating healthy exercise habits. The best way to make an exercise plan is to incorporate activities that fit your personal schedule and also make the activity fun and personalized to individual interests. There are many ways to strengthen your resolve when it comes to sticking with a workout plan according to Ryan Rhodes a professor of exercise and intention at the University of Victoria in British Columbia. He states that many people give up on their resolutions to exercise after the holidays because they fail to create sustainable exercise and workout plans based upon their lifestyles and interests. One way to stick with a daily exercise routine is to find something you enjoy doing like kayaking or skiing and look forward to doing them each day. Many people assume the only way to get in shape is by acquiring expensive gym memberships at locations that are inconvenient and unappealing or by going to get plastic surgery by Jennifer Walden. Taking your exercise outdoors or staying close to home during your workout will make the task much easier and less stressful. If you don’t enjoy the exercise it is much easier to give up on it. Another way to turn exercise into a daily habit is to plan for a time that fits with your sleep and work schedule. It is important to schedule your workout during the time of the day when you feel most invigorated.

Suffering from Sciatica? North American Spine has Your Back

For all you marathon-ers out there, I know you know what I’m talking about.

Almost everyone has experienced low back pain at some point in their lives. In fact, it is the number one cause of disability world wide. The causes can vary, but often the condition persists as the sufferer gets older. If you have had a low back injury or have long experienced chronic sciatic pain, North American Spine has everything you need under one roof.

North American Spine is an advocate for spreading the word via Twitter that sciatica itself is not a disease, but instead a term that’s used to describe the radiating pain that pulses through the buttocks and down through the legs. Some of the symptoms include pain in those areas that grows worse with sitting, burning or tingling down the leg, weakness or numbness or even difficulty moving the leg or foot, a constant pain on only one side of the buttock, and shooting pains that make standing for long periods difficult. Sciatica typically affects one side of the low body and can extend all the way down to the foot or toes. The severity of pain can be mild or extremely debilitating. It may be infrequent or constant. But it always has the potential to worsen as time goes on. Some of the damage caused by persistent sciatica can include foot and leg weakness, as previously mentioned, problems walking, but may include issues with bowel or bladder control, as well.

According to their Wikipedia page, North American Spine uses the AccuraScope procedure to relieve pressure caused by bulging disks. It is also used in effectively repairing tears on herniated discs. Through this invasive outpatient procedure, the patient often experience immediate relief from pain and can resume normal activities as quickly as the following day.

Though AccuraScope, the specialist inserts a thin endoscope, equipped with a high-definition camera and laser, into the spinal canal through a small opening at the base of the spine. With this advanced method, the specialist can diagnose and address more than one area of the spine with only one procedure. I saw a recent video on YouTube about how the procedure works, and it usually lasts between 30 and 40 minutes and requires only a single stitch and a small bandage.

North American Spine has numerous doctors, which specialize in the AccuraScope technique. If you are living with sciatic pain, don’t hesitate to get on Yelp and get it checked out. It’s time. I found out about them from Facebook and referred a fellow runner, long story short, she’s good as new. If AccuraScope is the right choice of for you, you may be back to your old self in less than a week.

Cutting Calories Can Keep you Younger, New Study Says

A new study has found out that, reducing the intake of calories can help people reduce aging and prevent chronic ailments in mammals.

The beneficial effects of calorie reduction in laboratory animals have been known in the last 80 years. However, it is in the last decade that scientists have tried to examine this fact in humans.

NYU Langone Medical Center carried out the new study. The neuroscientists examined female mice and came up with a conclusion that taking diet with less calories affects hundreds of genes linked to memory formation and aging. The study further revealed that a 30 percent cut on foods rich in calories can stop the expression of those genes.

The study’s senior investigator, Prof. Stephen D. Ginsberg said that this study is different from other studies because the investigators analyzed the impacts of diets in more than 10,000 genes. The professor also pointed that calorie restriction is not the main cause of staying young but he did add evidence to show diet plays a major role in aging. These findings confirm what Rod Rohrich teaches patients about diet, beauty, and health.

The researchers used female mice because they are more prone to dementia than their male counterparts. They fed the rodents with food with 30 percent less calories than the other mice.

The investigators then remove tissues from the rodents’ hippocampal region, an area which is mostly affected by Alzheimer’s tissue and memory loss. The scientists found out that the restricted calorie intake reduced the effects of aging on 882 genes in the hippocampal region.